Cancer and Blood Disorders

Show Only Open Trials
1.

Non-Comparative, Two-Cohort, Single-Arm, Open-Label, Phase 2 Study of Nivolumab (BMS-936558) in classical Hodgkin Lymphoma (cHL) Subjects after Failure of Autologous Stem Cell Transplant (ASCT)

  • Study Status: Open to Enrollment
  • Sponsor: Bristol-Myers Squibb
  • Disease Status and/or Stage: classical Hodgkin Lymphoma
  • Protocol ID: WCMC IRB #1406015182; Sponsor Protocol #CA209-205; ClinicalTrials.gov #NCT02181738
2.

Study of Nivolumab in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) That Have Either Failed or Are Not Eligible for Autologous Stem Cell Transplant

  • Study Status: Open to Enrollment
  • Sponsor: Bristol-Myers Squibb
  • Disease Status and/or Stage: Diffuse Large B-Cell Lymphoma
  • Protocol ID: WCMC IRB #1402014779; Sponsor Protocol #CA209-139; ClinicalTrials.gov #NCT02038933
3.

Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Ibrutinib or Placebo in Combination With Rituximab in Subjects with Previously Treated Waldenstrom's Macroglobulinemia

  • Study Status: Open to Enrollment
  • Sponsor: Pharmacyclics, Inc.
  • Disease Status and/or Stage: Previously Treated Waldenstrom's Macroglobulinemia
  • Protocol ID: WCMC IRB #1404015017; Sponsor Protocol #PCYC-1127; ClinicalTrials.gov #NCT02165397
4.

Phase Ib Multicenter Dose-finding and Safety Study of GDC-0199 and Obinutuzumab in Patients with Relapsed or Refractory or Previously Untreated Chronic Lymphocytic Leukemia

  • Study Status: Open to Enrollment
  • Sponsor: Genentech
  • Disease Status and/or Stage: Relapsed, Refractory or Previously Untreated Chronic Lymphocytic Leukemia
  • Protocol ID: WCMC IRB #1309014345; Sponsor Protocol #GP28331; ClinicalTrials.gov #NCT01685892
5.

Phase 1, Multicenter, Open-label, dose escalation Study of ACP-196 in Subjects with Chronic Lymphocytic Leukemia

  • Study Status: Open to Enrollment
  • Sponsor: Acerta Pharma
  • Disease Status and/or Stage: Chronic Lymphocytic Leukemia
  • Protocol ID: WCMC IRB #1311014537; Sponsor Protocol #ACE-CL-001; ClinicalTrials.gov #NCT02029443
6.

Phase 2 Open-Label Study of the Efficacy of ABT-199 in Subjects with Relapsed or Refractory Chronic Lymphocytic Leukemia Harboring the 17p Deletion

  • Study Status: Open to Enrollment
  • Sponsor: AbbVie
  • Disease Status and/or Stage: Relapsed or Refractory Chronic Lymphocytic Leukemia
  • Protocol ID: WCMC IRB #1308014231; Sponsor Protocol #M13-982; ClinicalTrials.gov #NCT01889186
7.

Rituximab, Bendamustine Hydrochloride, and Bortezomib followed by Rituximab and Lenalidomide in treating older patients with previously untreated Mantle Cell Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Eastern Cooperative Oncology Group
  • Disease Status and/or Stage: Mantle Cell Lymphoma
  • Protocol ID: WCMC IRB #1207012759; Sponsor Protocol #ECOG-E1411; ClinicalTrials.gov #NCT01415752
8.

Randomized Multi-center Pivotal Study of CDX-011 in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer (The "METRIC" Study)

  • Study Status: Open to Enrollment
  • Sponsor: Celldex Therapeutics, Inc.
  • Disease Status and/or Stage: Triple Negative Breast Cancer
  • Protocol ID: WCMC IRB #1403014844; Sponsor Protocol #CDX011-04
9.

Randomized, Open Label, Phase 2 Study of Selinexor (KPT-330) vs Physician's Choice in Patients Greater Than or Equal to 60 Years Old w/Relapsed/Refractory AML who are Ineligible for Intensive Chemo and/or Transplant

  • Study Status: Open to Enrollment
  • Sponsor: Kayorpham Therapeutics, Inc.
  • Disease Status and/or Stage: Acute Myeloid Leukemia
  • Protocol ID: WCMC IRB #1405015140; Sponsor Protocol #KCP-330-008; ClinicalTrials.gov #NCT02088541
10.

Dose Escalation and Cohort Expansion Study of TEN-010 in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

  • Study Status: Open to Enrollment
  • Sponsor: Tensha Therapeutics, Inc.
  • Disease Status and/or Stage: Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
  • Protocol ID: WCMC IRB #1409015842; Sponsor Protocol #TEN-010-004
11.

ANCHOR: Anal Cancer/HSIL Outcomes Research Study

  • Study Status: Open to Enrollment
  • Sponsor: National Cancer Institute Office of HIV and AIDS Malignancy (OHAM)
  • Disease Status and/or Stage: HIV Positive; Anal Cancer
  • Protocol ID: WCMC IRB #1407015335; Sponsor Protocol #A01; ClinicalTrials.gov #NCT02135419
12.

A Pilot Study to Evaluate Immunologic Biomarkers of Treatment Response and Disease Activity in Hodgkin Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: New York University Cancer Institute
  • Disease Status and/or Stage: Hodgkin Lymphoma
  • Protocol ID: WCMC IRB #1305013885; Sponsor Protocol #S12-02437
13.

A Single-Arm, Open-Label Phase 2 Study of Nivolumab (BMS-936558) in Subjects with Relapsed or Refractory Follicular Lymphoma (FL)

  • Study Status: Open to Enrollment
  • Sponsor: Bristol-Myers Squibb
  • Disease Status and/or Stage: Relapsed or Refractory Follicular Lymphoma
  • Protocol ID: WCMC IRB #1402014780; Sponsor Protocol #CA209-140; ClinicalTrials.gov #NCT02038946
14.

Multicenter Phase 2 Study of Single-Agent Filanesib (ARRY-520) in Patients With Advanced Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Array BioPharma Inc.
  • Disease Status and/or Stage: Advanced Multiple Myeloma
  • Protocol ID: WCMC IRB #1404014976; Sponsor Protocol #520-215
15.

Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839 in Patients with Advanced and/or Treatment-Refractory Hematological Malignancies

  • Study Status: Open to Enrollment
  • Sponsor: Calithera Biosciences
  • Disease Status and/or Stage: Non-Hodgkins Lymphoma; Waldenstrom's Macroglobulinemia; Multple Myeloma; Diffuse Large B-Cell Lymphoma; B-Cell NHL
  • Protocol ID: WCMC IRB #1404014998; Sponsor Protocol #CX-839-002
16.

An Open Label, Phase 1b, Study of ACP-196 in Subjects with Relapsed or Refractory de Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma (DLBCL)

  • Study Status: Open to Enrollment
  • Sponsor: Acerta Pharma BV
  • Disease Status and/or Stage: Diffuse Large B-cell Lymphoma
  • Protocol ID: WCMC IRB #1407015285; Sponsor Protocol #ACE-LY-002
17.

An Extension Study to Investigate the Safety and Durability of Clinical Activity of CAL-101 in Patients with Hematologic Malignancies

  • Study Status: Open to Enrollment
  • Sponsor: Gilead Sciences
  • Disease Status and/or Stage: Hematologic (blood) malignancies
  • Protocol ID: WCMC IRB #1003010934; Sponsor Protocol #101-99; Clinicaltrials.gov # NCT01090414
18.

Open-label, Phase 1b Study of ACP 196 in Subjects with Waldenstrom Macroglobulinemia

  • Study Status: Open to Enrollment
  • Sponsor: Acerta Pharma
  • Disease Status and/or Stage: Waldenstrom Macroglobulinemia
  • Protocol ID: WCMC IRB #1407015279; Sponsor Protocol #ACE-WM-001; ClinicalTrials.gov #NCT02180724
19.

Long-term Safety Study Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in B cell Lymphoma and Chronic Lymphocytic Leukemia (PCYC-1103)

  • Study Status: Open to Enrollment
  • Sponsor: Pharmacyclics
  • Disease Status and/or Stage: B-cell lymphoma & chronic lymphocytic leukemia
  • Protocol ID: WCMC IRB #1102011519; Sponsor Protocol #PCYC-1103-CA; Clinicaltrials.gov #NCT01109069
20.

A Study of IPI-145 and Ofatumumab in Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma previously enrolled in Study IPI-145-07

  • Study Status: Open to Enrollment
  • Sponsor: Infinity Pharmaceuticals, Inc.
  • Disease Status and/or Stage: Chronic lymphocytic leukemia/small lymphocytic lymphoma
  • Protocol ID: WCMC IRB #1312014602; Sponsor Protocol #IPI-145-12; Clinicaltrials.gov #NCT02004522
21.

Phase 3 Study of IPI-145 versus Ofatumumab in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Infinity Pharmaceuticals, Inc.
  • Disease Status and/or Stage: Relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma
  • Protocol ID: WCMC IRB #1312014601; Sponsor Protocol #IPI-145-07; Clincaltrials.gov #NCT02004522
22.

An Expanded Access Protocol for Idelalisib in Combination with Rituximab for Relapsed, Previously Treated Subjects with Chronic Lymphocytic Leukemia

  • Study Status: Closed to Enrollment
  • Sponsor: Gilead Sciences
  • Disease Status and/or Stage: Chronic lymphocytic leukemia
  • Protocol ID: WCMC IRB #1402014784; Sponsor Protocol #GS-US-312-1325; Clinicaltrials.gov #NCT02136511
23.

Gilead 0119: A Phase 3, Randomized, Controlled Study Evaluating the Efficacy and Safety of GS 1101 (CAL-101) in Combination with Ofatumumab for Previously Treated Chronic Lymphocytic Leukemia

  • Study Status: Closed to Enrollment
  • Sponsor: Gilead Sciences
  • Disease Status and/or Stage: Chronic lymphocytic leukemia
  • Protocol ID: WCMC IRB #1306013998; Sponsor Protocol #GS-US-312-0119; Clinicaltrials.gov #NCT01659021
24.

Phase I, Multicenter, Open-label and Dose-escalation Study of ACP-196 in Subjects with Chronic Lymphocytic Leukemia

  • Study Status: Open to Enrollment
  • Sponsor: Acerta Pharma
  • Disease Status and/or Stage: Chronic lymphocytic leukemia
  • Protocol ID: WCMC IRB #1311014537; Sponsor Protocol #ACE-CL-001; Clinicaltrials.gov #NCT02029443
25.

Randomized, Open-label, Phase 3 Trial of A+AVD Versus ABVD as Frontline Therapy in Patients with Advanced Classical Hodgkin Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Millennium Pharmaceuticals
  • Disease Status and/or Stage: Advanced classical hodgkin lymphoma
  • Protocol ID: WCMC IRB Protocol #1308014217; Sponsor Protocol # C25003; ClinicalTrials.gov #NCT01712490
26.

A Multicenter Open-Label, Randomized Phase 1b/2, Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination with Lenalidomide, with and without Rituximab in Subjects with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Pharmacyclics
  • Disease Status and/or Stage: Relapsed or Refractory (not responding to previous treatment) Diffuse Large B-cell Lymphoma
  • Protocol ID: WCMC IRB #1402014746; Sponsor Protocol #PCYC-1123-CA; Clinicaltrials.gov #NCT02077166
27.

A Multicenter, Open-Label, Phase 2 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Subjects with Relapsed/Refractory Marginal Zone Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Pharmacyclics
  • Disease Status and/or Stage: Marginal Zone Lyphoma
  • Protocol ID: WCMC IRB #1402014740; Sponsor Protocol #PCYC-1121-CA; Clinicaltrials.gov #NCT01980628
28.

A Phase 2 Study of IPI-145 in Subjects with Refractory Indolent Non-Hodgkin Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Infinity
  • Disease Status and/or Stage: Refractory (not responding to previous treatment) Non-Hodgkins Lyphoma
  • Protocol ID: WCMC IRB #1310014419; Sponsor Protocol #IPI-145-06; Clinicaltrials.gov #NCT01882803
29.

A phase I open-label, dose escalation study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK2816126 in subjects with relapsed/refractory diffuse large B cell and transformed follicular lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: GSK
  • Disease Status and/or Stage: Relapsed or Refractory (not responding to previous treatment) Diffuse Large B-cell Follicular Lymphoma
  • Protocol ID: WCMC IRB #1401014678; Sponsor Protocol #117208; Clinicaltrials.gov #NCT02082977
30.

PCI-32765 (Ibrutinib) in Patients with Newly Diagnosed non-Germinal Center B-Cell subtype of Diffuse Large B-Cell Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Janssen
  • Disease Status and/or Stage: Newly Diagnosed Diffuse Large B-Cell Lymphoma
  • Protocol ID: WCMC IRB #1309014328; Sponsor Protocol #PCI-32765DBL3001; Clinicaltrials.gov #NCT01855750
31.

A Phase 2 Open Label Study to Investigate the Efficacy of Autologous EBV-specific T cells for the Treatment of Patients with Aggressive Extranodal NK/T-cell Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Cell Medica, Inc.
  • Disease Status and/or Stage: Extranodal NK/T-cell Lymphoma
  • Protocol ID: WCMC IRB #1403014842; Sponsor Protocol #CM-2013-01; Clinicaltrials.gov # NCT01948180
32.

Phase 3 Study Comparing Daratumumab, Lenalidomide, and Dexamethasone (DRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects with Relapsed or Refractory Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Janssen Research & Development, LLC
  • Disease Status and/or Stage: Relapsed or Refractory (not responding to previous treatment) Multiple Myeloma
  • Protocol ID: WCMC IRB #1407015265; Sponsor Protocol #54767414MMY3003
33.

A Multicenter, Open-Label, Phase 2 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination with Rituximab in Previously Untreated Subjects with Follicular Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Pharmacyclics
  • Disease Status and/or Stage: Untreated Follicular Lymphoma
  • Protocol ID: WCMC IRB # 1402014785
34.

A Phase I/II Study of Pomalidomide (CC-4047®), Dexamethasone and Romidepsin in Patients with Relapsed or Refractory Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Investigator
  • Disease Status and/or Stage: Relapsed or Refractory Multiple Myeloma
35.

A Phase 1 Open-Label Study of the Safety and Efficacy of PD 0332991 (Palbociclib) in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Investigator
  • Disease Status and/or Stage: Relapsed or Refractory Multiple Myeloma
  • Protocol ID: WCMC IRB # 1306014004
36.

Phase 1b/3 Multicenter Study of Oprozomib, Pomalidomide, and Dexamethasone in Primary Refractory or Relapsed and Refractory Multiple Myeloma Subjects

  • Study Status: Open to Enrollment
  • Sponsor: Onxy
  • Disease Status and/or Stage: Primary Refractory or Relapsed and Refractory Multiple Myeloma
  • Protocol ID: WCMC IRB # 1310014409
37.

A Multicenter Phase 1/2b Study of the Bruton's Tyrosine Kinase Inhibitor, Ibrutinib (PCI-32765), in Combination with Carfilzomib (Kyprolis™) in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Pharmacyclics
  • Disease Status and/or Stage: Relapsed or Refractory Multiple Myeloma
  • Protocol ID: WCMC IRB # 1311014525
38.

Autologous Stem Cell Transplant With Pomalidomide (CC-4047®) Maintenance Versus Continuous Pomalidomide / Dexamethasone Salvage Therapy in Relapsed or Refractory Multiple Myeloma: A Phase 2 Open-Label Randomized Study by Tristate Consortium

  • Study Status: Open to Enrollment
  • Sponsor: Celgene; Memorial Sloan Kettering Cancer Center
  • Disease Status and/or Stage: Relapsed/Refractory Multiple Myeloma
  • Protocol ID: WCMC IRB #1303013631
40.

An Open-Label, Multicenter, Phase 2 Study of Oral MLN9708 in Adult Patients with Relapsed and/or Refractory Follicular Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Millennium Pharmaceuticals
  • Disease Status and/or Stage: Relapsed or refractory follicular lymphoma
41.

A Phase 2, Multi-center Study of High Dose Chemotherapy with Autologous Stem Cell Transplant followed by Maintenance Therapy with romidepsin for the Treatment of T-cell Non-Hodgkin Lymphoma (NHL)

  • Study Status: Open to Enrollment
  • Sponsor: Memorial Sloan Kettering Cancer Center
  • Disease Status and/or Stage: Non-Hodgkin's Lymphoma
42.

A Phase I Study of the Safety, Pharmacokinetics and Pharmacodynamics of Escalating Doses of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients with Advanced Hematological Malignancies

  • Study Status: Open to Enrollment
  • Sponsor: NPM Pharma
  • Disease Status and/or Stage: Advanced hematologic malignancies
  • Protocol ID: WCMC IRB #1310014371; Sponsor Protocol #KCP-330-001; ClinicalTrials.gov #NCT01607892
43.
46.

GO27983: A Phase Ib/II Study of GDC-0068 or GDC-0980 with Abiraterone Acetate versus Abiraterone Acetate in Patients with Castration-Resistant Prostate Cancer Previously Treated with Docetaxel-Based Chemotherapy

  • Study Status: Open to Enrollment
  • Sponsor: Genentech
  • Disease Status and/or Stage: Metastatic or Advanced Prostate Cancer
  • Protocol ID: GO27983
47.
48.

A Phase 2, Open-label, Multicenter Study of PSMA ADC in Subjects with Metastatic Castration-resistant Prostate Cancer (mCRPC)

  • Study Status: Open to Enrollment
  • Sponsor: PSMA Development Company
  • Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
  • Protocol ID: PSMA ADC 2301
49.

S1216: Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: SWOG
  • Disease Status and/or Stage: Metastatic Prostate Cancer
  • Protocol ID: S1216
50.

CALGB 30801: A Randomized Phase III Double Blind Trial Evaluating Selective COX-2 Inhibition in COX-2 Expressing Advanced Non-Small Cell Lung Cancer

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Non Small Cell Lung Cancer (NSCLC)
  • Protocol ID: CALGB 30801
51.

Gilead 0125: A Study Evaluating the Efficacy and Safety of Idelalisib(GS-1101) in Combination With Bendamustine and Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas

  • Study Status: Open to Enrollment
  • Sponsor: Gilead
  • Disease Status and/or Stage: Previously Treated Indolent non-Hodgkin Lymphoma
  • Protocol ID: Gilead 0125
52.

Gilead 0124: A Study Evaluating the Efficacy and Safety of Idelalisib (GS-1101) in Combination With Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas

  • Study Status: Open to Enrollment
  • Sponsor: Gilead
  • Disease Status and/or Stage: Previously Treated Indolent non-Hodgkin Lymphoma
  • Protocol ID: Gilead 0124
55.

Clinical Performance, Efficacy and Safety of the DigniCap System, a Scalp Hypothermia System, in Preventing Chemotherapy Induced Alopecia in Patients with Early Stage Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Dignitana AB
  • Disease Status and/or Stage: Stage I or II Breast Cancer
  • Protocol ID: DIG-001
56.

MLN9708 plus Lenalidomide and Dexamethasone versus Placebo plus Lenalidomide and Dexamethasone in Adult Patients with Newly Diagnosed Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Millennium
  • Disease Status and/or Stage: Untreated Multiple Myeloma
  • Protocol ID: C16014
57.

Analysis of Hematopoietic Progenitor Cells and Endothelial Progenitor Cells to Predict Early Relapse of Treated Non-Small-Cell Lung Cancer (NSCLC): A Pilot Study

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Non-Small Cell Lung Cancer
58.

A051103: A Phase I Study of Rituximab, Lenalidomide, and Ibrutinib in Previously Untreated Follicular Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: Alliance for Clinical Trials in Oncology
  • Disease Status and/or Stage: Untreated Follicular Lymphoma
  • Protocol ID: A051103
59.

Alliance A051202: A Phase I Trial of Lenalidomide, Rituximab, and Idelalisib in Recurrent Follicular Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: Alliance for Clinical Trials in Oncology
  • Disease Status and/or Stage: Recurrent Follicular non-Hodgkin Lymphoma
  • Protocol ID: A051202
60.

CALGB 100801: Phase II Study of the Addition of Azacitidine to Reduced-Intensity Conditioning Allogeneic Transplantation for Myelodysplasia (MDS) and Older patients With AML

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Acute Myeloid Leukemia and Myelodysplasia
  • Protocol ID: CALGB 100801
61.

A Phase Ib/IIa Study of Romidepsin in Combination with Lenalidomide in Adults with Relapsed or Refractory Lymphomas and Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Memorial Sloan-Kettering Cancer Center
  • Disease Status and/or Stage: Relapsed or Refractory Lymphoma and Multiple Myeloma
62.

A Prospective, Longitudinal, Observational Study in Newly Diagnosed Multiple Myeloma (MM) Patients to Assess the Relationship between Patient Outcomes, Treatment Regimens and Molecular Profiles

  • Study Status: Open to Enrollment
  • Sponsor: Multiple Myeloma Research Foundation
  • Disease Status and/or Stage: Untreated Multiple Myeloma
63.

An Open-Label Treatment Use Protocol for Ibrutinib (PCI-32765) in Subjects with Relapsed or Refractory Mantle Cell Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: Janssen and Pharmacyclics
  • Disease Status and/or Stage: Relapsed or Refractory Mantle Cell Lymphoma
  • Protocol ID: PCI-32765MCL4001
65.

A Phase III Study of Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic HER2-Negative And Met-Positive Gastroesophageal Cancer (MetGastric)

  • Study Status: Open to Enrollment
  • Sponsor: Genentech
  • Disease Status and/or Stage: Metastatic Gastric Cancer
  • Protocol ID: YO28322
66.

LUX-Lung 8: A randomized, open-label Phase III trial of afatinib versus erlotinib in patients with advanced squamous cell carcinoma of the lung as second-line therapy following first-line platinum-based chemotherapy

  • Study Status: Closed to Enrollment
  • Sponsor: Boehringer Ingelheim Pharmaceuticals
  • Disease Status and/or Stage: Previously Treated Advanced Squamous Cell Lung Cancer
67.
68.

A Randomized Controlled Study of Extracorporeal Photopheresis (ECP) Therapy with UVADEX™ for the Treatment of Patients with Moderate to Severe Chronic Graft versus Host Disease (cGVHD)

  • Study Status: Open to Enrollment
  • Sponsor: Therakos
  • Disease Status and/or Stage: Moderate to Severe Graft-versus-Host Disease (GVHD)
69.

RDCRN 6503: Targeted Therapy of Bronchiolitis Obliterans Syndrome

  • Study Status: Open to Enrollment
  • Sponsor: NIH, GVHD Consortium
  • Disease Status and/or Stage: Bronchiolitis Obliterans Syndrome (BOS) after Hematopoietic Cell Transplant (HCT)
70.

RDCRN 6502: A Randomized Phase II Study of Imatinib and Rituximab for Cutaneous Sclerosis after Allogeneic Hematopoietic Cell Transplantation

  • Study Status: Open to Enrollment
  • Sponsor: NIH, GVHD Consortium
  • Disease Status and/or Stage: Cutaneous Sclerosis after Hematopoietic Cell Transplant (HCT); blood disorders; rituximab; imatinib; Sebastian Mayer MD; Weill Cornell Bone Marrow Transplant; stem cell transplant; New York Presbyterian Hospital
  • Protocol ID: RDCRN 6502
71.

Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)

  • Study Status: Open to Enrollment
  • Sponsor: Fresenius Biotech GmbH
  • Disease Status and/or Stage: Acute Lymphocytic Leukemia (ALL), Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
  • Protocol ID: IV-ATG-SCT-01
72.

A Randomized, Open-Label, Phase 3 Study of BMS-936558 vs Everolimus in Subjects with Advanced or Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy

  • Study Status: Open to Enrollment
  • Sponsor: Bristol-Myers Squibb
  • Disease Status and/or Stage: Advanced or Metastatic Kidney Cancer
  • Protocol ID: BMS CA209-025-041
73.

A Phase 1 Dose Escalation Study of OMP-52M51 in Subjects with Lymphoid Malignancies

  • Study Status: Open to Enrollment
  • Sponsor: OncoMed
  • Disease Status and/or Stage: Relapsed or Refractory Lymphoid Malignancies, Including Chronic Lymphocytic Leukemia (CLL), Mantle Cell Lymphoma (MCL), Diffuse Large B-cell Lymphoma (DLBCL), Transformed Mycosis Fungoides (MF), or Sezary Syndrome
  • Protocol ID: 52M51-001
74.

An Open-label, Multicenter, Single-arm, Phase 2 Study of PCI-32765 (Ibrutinib) in Subjects with Refractory Follicular Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: Janssen
  • Disease Status and/or Stage: Refractory Follicular Lymphoma
  • Protocol ID: PCI-32765FLR2002
75.

A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs. Prednisone in Metastatic Castration-resistant Prostate Cancer Patients who have Received Prior Docetaxel and Prior Abiraterone or MDV3100

  • Study Status: Open to Enrollment
  • Sponsor: Exelixis
  • Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
  • Protocol ID: XL184-307
76.

S1117: A Randomized Phase II Study of Azacitidine in Combination with Lenalidomide vs. Azacitidine Alone vs. Azacitidine in Combination with Vorinostat for Higher-Risk Myelodysplatic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Higher Risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML)
  • Protocol ID: S1117
77.

A phase II study of brentuximab vedotin as salvage therapy for Hodgkin Lymphoma prior to autologous hematopoietic stem cell transplantation

  • Study Status: Open to Enrollment
  • Sponsor: City of Hope
  • Disease Status and/or Stage: Relapsed or Refractory to One Frontline Induction Therapy
79.

A Phase 2, Randomized, Open-Label Study of the Safety and Efficacy of Two Doses of Quizartinib (AC220; ASP2689) in Subjects with FLT3-ITD Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

  • Study Status: Closed to Enrollment
  • Sponsor: Astellas Pharma
  • Disease Status and/or Stage: Relapsed or Refractory Acute Myeloid Leukemia (AML); AC220; ASP2689; blood cancer treatment; Ellen Ritchie; Gail Roboz; Weill Cornell Leukemia: New York Presbyterian Hospital
81.

Phase 3 randomized study to evaluate the substitution of Marqibo for standard vincristine sulfate injection in combination chemotherapy for subjects ≥ 60 yrs old w/ newly diagnosed ALL

  • Study Status: Open to Enrollment
  • Sponsor: Talon Therapeutics
  • Disease Status and/or Stage: Newly Diagnosed ALL, Age 60 and Older
84.

A Phase 2 Study of LY2784544 in Patients with Myeloproliferative Neoplasms

  • Study Status: Open to Enrollment
  • Sponsor: Ely Lilly
  • Disease Status and/or Stage: Polycythemia Vera (PV), Essential Thrombocythemia (ET), or Myelofibrosis (MF)
85.

Phase II randomized controlled trial of pegylated interferon alpha-2b in early primary myelofibrosis

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Low or Intermediate Stage Primary Myelofibrosis (PMF)
86.

Combined Tretinoin and Arsenic Trioxide for Patients With Newly Diagnosed Acute Promyelocytic Leukemia Followed by Risk-Adapted Postremission Therapy

  • Study Status: Closed to Enrollment
  • Sponsor: Memorial Sloan-Kettering Cancer Center
  • Disease Status and/or Stage: Newly Diagnosed Acute Promyelocytic Leukemia
87.

A Phase II Trial of the Aurora Kinase A Inhibitor MLN8237 in Patients with Metastatic Castrate Resistant and Neuroendocrine Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic (advanced) Castrate Resistant & Neuroendocrine Prostate Cancer
  • Protocol ID: WCMC IRB #1210013164
88.
89.

A Phase 3 Randomized, Open-Label Study of Ponatinib versus Imatinib in Adult Patients with Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

  • Study Status: Closed to Enrollment
  • Sponsor: Ariad
  • Disease Status and/or Stage: Newly Diagnosed Chronic Myeloid Leukemia
  • Protocol ID: AP24534-12-301
90.

An Open Label Multicenter Phase 2 Window of Opportunity Study Evaluating Ganetespib (STA-9090) Monotherapy in Women with Previously Untreated Metastatic HER2 Positive or Triple Negative Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Synta
  • Disease Status and/or Stage: Previously Untreated Metastatic HER2-Positive or Triple Negative Breast Cancer
91.

A Double-blind, Randomized Phase II Trial of Active Immunotherapy with Globo H-KLH (OPT-822) in Subjects with Metastatic Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Optimer Biotechnology
  • Disease Status and/or Stage: Metastatic Breast Cancer
92.

A Phase I/II Trial of Temsirolimus Plus Neratinib for Subjects with Metastatic HER2-Amplified or Triple Negative Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Puma
  • Disease Status and/or Stage: HER2-Positive Metastatic Breast Cancer
93.

Phase I Study of IMMU-132 (hRS7-SN38 Antibody Drug Conjugate) in Patients with Epithelial Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Immunomedics
  • Disease Status and/or Stage: Metastatic Epithelial Cancer
94.

A Phase II Study of Daily Alternating Thalidomide and Lenalidomide Therapy Plus Rituximab (THRiL) as Initial Treatment for Patients with CLL

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Untreated CLL
95.

A Study of Trastuzumab Emtansine Versus Taxane in Patients With Advanced Gastric Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Hoffmann-La Roche/Genentech
  • Disease Status and/or Stage: Advanced or Metastatic HER2-Positive Gastric or GEJ Cancer
  • Protocol ID: BO27952
96.

A Prospective Randomized Trial Comparing Three Different Peripheral Stem Cell Mobilization Regimens in Patients With Symptomatic Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Mutliple Myeloma
97.

The BEACON Study (Breast Cancer Outcomes With NKTR-102)

  • Study Status: Open to Enrollment
  • Sponsor: Nektar Therapeutics
  • Disease Status and/or Stage: Locally Recurrent or Metastatic Breast Cancer Previously Treated with Cytotoxic Chemotherapy
98.

A multicenter safety study of unlicensed, investigational cryopreserved cord blood units (CBUs) manufactured by the National Cord Blood Program (NCBP) and provided for unrelated hematopoietic stem cell transplantation of pediatric and adult patients

  • Study Status: Open to Enrollment
  • Sponsor: National Cord Blood Program
  • Disease Status and/or Stage: Hematologic Malignancies and Other Indications Receiving Allogeneic Hematopoieic Stem Cell Transplant
99.

A Multicenter Phase 1-2 Study of MLN8237, an Oral Aurora A Kinase Inhibitor, in Patients with Relapsed or Refractory Aggressive B-Cell Lymphoma Treated with Rituximab and Vincristine

  • Study Status: Closed to Enrollment
  • Sponsor: Millennium
  • Disease Status and/or Stage: Relapsed/Refractory Diffuse Large B-Cell Lymphoma, Transformed Follicular Lymphoma, Mantle Cell Lymphoma or Burkitt Lymphoma
  • Protocol ID: C14011
101.

A phase III trial of adjuvant chemotherapy following chemoradiation as primary treatment for locally advanced cervical cancer compared to chemoradiation alone: THE OUTBACK TRIAL

  • Study Status: Open to Enrollment
  • Sponsor: Gynecologic Oncology Group; National Cancer Institute
  • Disease Status and/or Stage: Locally Advanced Cervical Cancer
102.

Phase II Trial of Combination Pemetrexed (Alimta) and Carboplatin (Paraplatin) in Platinum Sensitive Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: Montefiore Medical Center
  • Disease Status and/or Stage: Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer
103.

A Phase Ib Study of Fractionated 90Y-hPAM4 with or without Gemcitabine in Patients with Metastatic Pancreatic Cancer who Received at Least Two Prior Treatments

  • Study Status: Closed to Enrollment
  • Sponsor: Immunomedics
  • Disease Status and/or Stage: Stage IV Metastatic Pancreatic Cancer
  • Protocol ID: IM-T-hPAM4-03
104.

Lenalidomide plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Relapsed/Refractory Multiple Myeloma
105.

An Open-Labeled, Multicenter Phase II Study of Cabazitaxel in Refractory Metastatic Gastric or Gastroesophageal Adenocarcinoma

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic Gastric or Gastroesophageal (GEJ) Cancer
106.

N093B: Phase I/II Study of Panobinostat (LBH589) and Letrozole in Patients with Triple Negative Metastatic Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Cancer Trials Support Unit (CTSU)
  • Disease Status and/or Stage: Triple Negative Metastatic Breast Cancer
  • Protocol ID: N093B
107.

PRESENT: Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVaxâ„¢ Treatment

  • Study Status: Open to Enrollment
  • Sponsor: Galena Biopharma
  • Disease Status and/or Stage: HER2 1+/2+, Node Positive Breast Cancer
108.

A Phase 3, Randomized, Two-Arm, Open-Label, Multicenter, International Trial of Alisertib (MLN8237) or Investigator's Choice (Selected Single Agent) in Patients with Relapsed or Refractory Peripheral T-Cell Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Millennium
  • Disease Status and/or Stage: Relapsed/Refractory Peripheral T-Cell Lymphoma
  • Protocol ID: C14012
109.

A Phase II Study of Sequential Carfilzomib, Clarithromycin, Lenalidomide, and Dexamethasone (Car-BiRD) Therapy for Subjects with Newly Diagnosed Multiple Myeloma

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Newly Diagnosed Multiple Myeloma; No Previous Treatment
110.

An Open-label Phase 2 Study of ACE-041 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

  • Study Status: Closed to Enrollment
  • Sponsor: Acceleron
  • Disease Status and/or Stage: Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
111.

A Randomized study of Combined Haplo-identical Umbilical Cord Transplantation vs. Double Umbilical Cord Transplantation in Patients with Hematologic Malignancies

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Hematologic Malignancies in Need of Donor Stem Cell Transplant
112.

A Study of Trastuzumab in Combination With Cisplatin/Capecitabine Chemotherapy in Patients With HER2-Positive Metastatic Gastric or Gastro-Esophageal Junction Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Genentech/Roche
  • Disease Status and/or Stage: Metastatic Gastric Cancer
113.

BMT CTN 0903 - Allogeneic Hematopoietic Cell Transplant for Hematological Cancers and Myelodysplastic Syndromes in HIV-Infected Individuals

  • Study Status: Open to Enrollment
  • Sponsor: BMT-CTN
  • Disease Status and/or Stage: Hematologic Cancers and Myelosysplastic Syndromes in HIV-Positive People
  • Protocol ID: BMT CTN 0903
114.

CALGB 80702: A Phase III Trial of 6 versus 12 Treatments of Adjuvant Folfox Plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer

  • Study Status: Open to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Resected Stage III Colon Cancer
  • Protocol ID: CALGB 80702
115.

CALGB 50801: Phase II Trial of Response-Adapted Therapy Based on Positron Emission of Tomography (PET) for Bulky Stage I and Stage II Classical Hodgkin Lymphoma (HL)

  • Study Status: Open to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Bulky, Early Stage Hodgkin Lymphoma
116.

CALGB 50604: Phase II Trial of Response-Adapted Chemotherapy Based on Positron Emission Tomography for Non-Bulky Stage I and II Hodgkin Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Hodgkin Lymphoma, Stage IA, IB, IIA or IIB
  • Protocol ID: CALGB 50604
118.

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Idelalisib (GS-1101) in Combination with Rituximab for Patients with Previously Treated Chronic Lymphocytic Leukemia

  • Study Status: Closed to Enrollment
  • Sponsor: Gilead Sciences, Inc.
  • Disease Status and/or Stage: Previously Treated Chronic Lymphocytic Leukemia (CLL)
  • Protocol ID: 0116
119.

Single Arm Salvage Therapy With Pegylated Interferon Alfa-2a for Patients With High Risk Polycythemia Vera or High Risk Essential Thrombocythemia Who Are Either Hydroxyurea Resistant or Intolerant or Have Had Abdominal Vein Thrombosis

  • Study Status: Open to Enrollment
  • Sponsor: Myeloproliferative Disorders-Research Consortium
  • Disease Status and/or Stage: High Risk Polycythemia Vera; High Risk Essential Thrombocythemia
  • Protocol ID: MPD-RC 111
121.

Ruxolitinib (INCB018424) in Subjects With Primary Myelofibrosis, Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis

  • Study Status: Closed to Enrollment
  • Sponsor: Incyte Corporation
  • Disease Status and/or Stage: Primary Myelofibrosis; Post Essential Thrombocythemia-myelofibrosis; Post Polycythemia Vera-myelofibrosis
123.

CALGB 50901: A Phase II Trial of Ofatumumab (CALGB IND #112390) in Previously Untreated Follicular Non-Hodgkin's Lymphoma (NHL)

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Untreated Follicular Lymphoma
  • Protocol ID: CALGB 50901
125.

S1108: A Phase II Trial of the Aurora Kinase A Inhibitor MLN8237, in Relapsed or Refractory Peripheral T-Cell Non-Hodgkin Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: SWOG
  • Disease Status and/or Stage: Relapsed/Refractory Peripheral T-Cell non-Hodgkin Lymphoma
127.

CALGB 50904: A Randomized Phase II Trial of Ofatumumab and Bendamustine vs. Ofatumumab, Bortezomib (NSC #681239, IND #58443) and Bendamustine in Patients with Untreated Follicular Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Untreated Follicular Lymphoma
  • Protocol ID: CALGB 50904
128.

A Multicenter, Open-label, Phase 2, Safety and Efficacy Study of the Bruton's Tyrosine Kinase (Btk) Inhibitor, PCI-32765, in Subjects with Relapsed or Refractory De Novo diffuse Large B-Cell Lymphoma (PCYC 1106)

  • Study Status: Closed to Enrollment
  • Sponsor: Pharmacyclics
  • Disease Status and/or Stage: Relapsed or Refractory de Novo Diffuse Large B-cell Lymphoma (DLBCL)
129.

Clinical Database and Tissue Repository Collection Project for the Study of Waldenstrom's Macroglobulinemia

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
132.

CALGB 11002 - A Randomized Phase II Trial of Decitabine-Based Induction Strategies for Patients ≥ 60 Years Old With Acute Myeloid Leukemia (AML)

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB
  • Disease Status and/or Stage: Acute Myeloid Leukemia
133.

REO 017: A Phase 2 Study of Reolysin® in Combination with Gemcitabine for Patients with Advanced Pancreatic Adenocarcinoma

  • Study Status: Closed to Enrollment
  • Disease Status and/or Stage: Advanced or Metastatic Pancreatic Cancer
134.

A Phase II Study of Tetrathiomolybdate (TM) in patients with breast cancer at moderate to high risk of recurrence

  • Study Status: Closed to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: High-Risk Stage II Breast Cancer; Stage III Breast Cancer; Stage IV Breast Cancer in Remission
135.

Prospective Data Collection Among Women Using Cold Caps During TC Chemotherapy

  • Study Status: Open to Enrollment
  • Disease Status and/or Stage: Early-Stage Breast Cancer
137.

A Phase 1b Safety Study of Abiraterone Acetate (JNJ 212082) and Docetaxel in Subjects with Metastatic Castration-Resistant Prostate Cancer (mCRPC) (COU-AA-206)

  • Study Status: Open to Enrollment
  • Sponsor: Cougar Biotechnology
  • Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
138.

Phase II Study of Lenalidomide plus Rituximab in Patients with Previously Untreated Mantle Cell Lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Untreated Mantle Cell Lymphoma
139.

Phase I Study of Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy in Patients With Resectable Esophageal Cancer

  • Study Status: Closed to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Resectable Cancer of the Esophagus or Gastroesophageal Junction (GEJ)
141.

An Open-Label, Randomized, Phase 2 Study to Assess the Effectiveness of RCHOP With or Without VELCADE in Previously Untreated Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma Patients

  • Study Status: Closed to Enrollment
  • Sponsor: Millennium Pharmaceuticals
  • Disease Status and/or Stage: Previously untreated Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma
142.

Phase 1 Study of PD 0332991 Plus Bortezomib in Patients with Previously Treated Mantle Cell Lymphoma

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Mantle Cell Lymphoma (MCL)
143.

Treatment Decision Making in Elderly Patients with Hematological Malignancies: New Approaches to an Old Problem

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Hematological Malignancies
144.
145.

Phase III MultiCenter Randomized Controlled Study to Assess Efficacy and Safety of ON 01910.Na 72-Hr Continuous IV Infusion in MDS Patients With Excess Blasts Relapsing After or Refractory to or Intolerant to Azacitidine or Decitabine

  • Study Status: Closed to Enrollment
  • Sponsor: Onconova Therapeutics, Inc
  • Disease Status and/or Stage: Myelodysplastic Syndromes (MDS) Including RAEB and Chronic Myelomonocytic Leukemia (CMML)
146.

CALGB 10403: An Intergroup Phase II Clinical Trial for Adolescents and Young Adults With Untreated Acute Lymphoblastic Leukemia (ALL)

  • Study Status: Closed to Enrollment
  • Sponsor: CALGB; NCI; Eastern Cooperative Oncology Group; Southwest Oncology Group
  • Disease Status and/or Stage: Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
  • Protocol ID: CALGB 10403
147.

A Phase 1, Dose Escalation, Multicenter Study of Two Subcutaneous Regimens of SGI-110, a DNA Hypomethylating Agent, in Subjects With Intermediate-2 or High-Risk Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)

  • Study Status: Open to Enrollment
  • Sponsor: SuperGen
  • Disease Status and/or Stage: Intermediate-2 or high-risk Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)
148.

Pilot study of abbreviated chemotherapy based on early positron emission tomography in Hodgkin lymphoma

  • Study Status: Closed to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Untreated Hodgkin Lymphoma
149.

MPD-RC 108: Phase II, Randomized, Double-Blind, Placebo Controlled International Study of Clopidogrel and Aspirin for the Treatment of Polycythemia Vera

  • Study Status: Closed to Enrollment
  • Sponsor: Myeloproliferative Disorders-Research Consortium
  • Disease Status and/or Stage: Polycythemia Vera (PV)
151.

A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Cancer and Leukemia Group B, National Cancer Institute
  • Disease Status and/or Stage: High Risk, Clinically Localized Prostate Cancer
  • Protocol ID: CALGB 90203
152.

Radioimmunotherapy Phase I Dose-Escalation Studies in Prostate Cancer using 177Lu-J591 Antibody: Dose Fractionation Regimen

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic Prostate Cancer
154.

A Phase I Trial of Docetaxel/Prednisone plus Fractionated 177Lu-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients with Metastatic, Castrate-Resistant Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic Prostate Cancer
155.

A Phase III trial of short term androgen deprivation with pelvic lymph node or prostate bed only radiotherapy (SPPORT) in prostate cancer patients with a rising PSA after radical prostatectomy

  • Study Status: Open to Enrollment
  • Sponsor: Radiation Therapy Oncology Group, National Cancer Institute
  • Disease Status and/or Stage: Prostate Cancer After Radical Prostatectomy
156.

A Phase 1B, Open-Label, Dose Escalation Study Evaluating the Safety of BSI-201 in Combination with Chemotherapeutic Regimens in Subjects with Advanced Solid Tumors

  • Study Status: Closed to Enrollment
  • Sponsor: BiPar Sciences
  • Disease Status and/or Stage: Metastatic Pancreatic Cancer
157.

Chemotherapy and Radiation in Treating Patients With Stage 3 Non-Small Cell Lung Cancer (PROCLAIM)

  • Study Status: Open to Enrollment
  • Sponsor: Eli Lily & Co.
  • Disease Status and/or Stage: Unresectable, Locally Advance, Stage III Non-Small Cell Lung Cancer
158.

CALGB 140503: A Phase III Randomized Trial of Lobectomy versus Sublobar Resection for Small (<2cm) Peripheral Non-Small Cell Lung Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Cancer and Leukemia Group B, National Cancer Institute
  • Disease Status and/or Stage: Non-small Cell Lung Cancer
159.

A Phase I/II Study of Vorinostat in Combination with Isotretinoin in the Treatment of Patients with Advanced Renal Cell Carcinoma

  • Study Status: Closed to Enrollment
  • Sponsor: Weill Cornell Medical College, National Cancer Institute
  • Disease Status and/or Stage: Metastatic or Advanced Kidney Cancer
160.

A Phase I/II Trial of BAY 43-9006 plus Gemcitabine and Capecitabine in the Treatment of Patients with Advanced Renal Cell Carcinoma

  • Study Status: Closed to Enrollment
  • Sponsor: Weill Cornell Medical College, National Cancer Institute
  • Disease Status and/or Stage: Advanced, Unresectable and/or Metastatic Kidney Cancer
161.

ECOG 2805: A Randomized, Double-Blind Phase III Trial of Adjuvant Sunitinib versus Sorafenib versus Placebo in Patients with Resected Renal Cell Carcinoma (RCC)

  • Study Status: Closed to Enrollment
  • Sponsor: Eastern Cooperative Oncology Group
  • Disease Status and/or Stage: Renal Cell Cancer
162.

A Phase II Trial of Temsirolimus and Bevacizumab in Patients With Endometrial, Ovarian, Hepatocellular Carcinoma, Carcinoid and Islet Cell Cancer

  • Study Status: Closed to Enrollment
  • Sponsor: Mayo Clinic, National Cancer Institute
  • Disease Status and/or Stage: Locally Advanced, Recurrant or Metastatic disease
163.

A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients With Advanced Transitional Cell Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: Cancer and Leukemia Group B (CALGB); National Cancer Institute (NCI)
  • Disease Status and/or Stage: Advanced Transitional Cell Carcinoma
164.

A Phase I Study of 177Lu Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-591) in Patients with Nonprostate Metastatic Solid Tumors: A Pilot Study

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic Solid Tumor
165.
166.

Phase II study of ixabepilone in patients with metastatic breast cancer and a prospective evaluation of its effects on the ultrastructure of neurons

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College; Bristol-Myers Squibb
  • Disease Status and/or Stage: Metastatic Breast Cancer
167.

ACOSOG Z1072: A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: American College of Surgeons/National Cancer Institute
  • Disease Status and/or Stage: Invasive Breast Cancer
169.

A Phase II Study of Tetrathiomolydate (TM) in patients with breast cancer at moderate to high risk for recurrence

  • Study Status: Closed to Enrollment
  • Disease Status and/or Stage: Breast Cancer at moderate to high risk of recurrence (based on the number of lymph nodes); Stage 4 breast cancer without any evidence of disease

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